Linkage and substitution mapping on RNO1 using S and LEW rats.
The LOD plot for BP was obtained from the study of an F2(S x LEW) population. This is shown at the top followed by the cytogenetic and physical maps of RNO1 . End markers of congenic strains and current physical locations are shown with flanking bars. The physical locations of markers were obtained from the Rat Genome Database (http://www.rgd.mcw.edu) version 6.0. *The location for markers not mapped were determined using nearby markers chosen using the limits of the congenic strains. Congenic strains having a BP lowering effect are shown with a green bar. Congenic strains having no BP effect are shown with a black bar and a red bar indicates that the congenic strain has a BP increasing effect. All congenic strains except the ones currently reported are previously published [14, 16–19]. Vertical blue or orange lines collectively depict the reported QTL regions. The names of QTLs are depicted in the blue or orange horizontal bars along with their respective sizes.