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LASAG-mediated inhibition is NF-κB dependent.

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posted on 15.05.2020, 17:36 by Janine J. Wilden, Andre van Krüchten, Lutz Gieselmann, Eike R. Hrincius, Stefanie Deinhardt-Emmer, Karoline F. Haupt, Hannah F. Preugschas, Silke Niemann, Stephan Ludwig, Christina Ehrhardt

A549 human lung epithelial cells were left uninfected or were infected with IV PR8-M (MOI = 0.1) and/or superinfected with the S. aureus 6850 (MOI = 0.1) as described in the material and method section. After infection, cells were lysed to perform Western Blot analysis. Monitored are the protein amounts of phospho-p65, IV M1 and S. aureus PGN. ERK-2 served as loading control.

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