Knockdown of Girdin represses growth and metastasis of hepatoma cells.

https://doi.org/10.1371/journal.pone.0315534.g003
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posted on 2024-12-13, 18:32 authored by Tengda Huang, Hongying Chen, Hongyuan Pan, Tian Wu, Xiangyi Ren, Liwen Qin, Kefei Yuan, Fang He

<p>(A-B) RT-qPCR and western blot of the expression levels of Girdin in HepG2 cells transfected with negative control siRNA or siRNAs targeting Girdin. (C) Cell numbers of HepG2 cells were measured by cell culture monitoring system. (D) DNA replication of indicated HepG2 cells was examined by EdU assay. (E) Cell migration and invasion of HepG2 cells were measured by transwell migration and matrigel invasion assays, respectively. *p<0.05, **p<0.01.</p>

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