Ketamine decreases NSC viability in a dose-dependent manner.
NSCs were plated as single cells treated with 50 μM, 200 μM, 400 μM and 1 mM ketamine. To measure cell viability, intracellular ATP levels were measured after 24 hours. Data are shown as mean ±SEM (n = 22–35). Kruskal-Wallis followed by Dunn’s test was used. Differences were considered significant at P <0.05. * denotes P<0.05 compared with control.