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Kaplan–Meier analysis of disease-free survival of breast cancer patients dependent on the expression of mRNA coding for oestradiol metabolising enzymes

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posted on 31.12.2011, 04:35 authored by Noriko Yoshimura, Nobuhiro Harada, Ida Bukholm, Rolf Kåresen, Anne-Lise Børresen-Dale, Vessela N Kristensen

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Taken from "Intratumoural mRNA expression of genes from the oestradiol metabolic pathway and clinical and histopathological parameters of breast cancer"

Breast Cancer Research 2003;6(2):R46-R55.

Published online 11 Dec 2003


Copyright © 2004 Yoshimura et al., licensee BioMed Central Ltd. This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the article's original URL.

CYP19 (aromatase) using the conventional, adipose tissue-specific first exon (curve 1), abnormally using the ovarian-specific first exon (curve 2), and with the 0-null expression (curve 0). Steroid sulfatase with expression below (curve 1) and above (curve 2) the median. Oestrogen receptor (ER)α below (curve 1) and above (curve 2) the median. ERβ below (curve 2) and above (curve 1) the median.