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Intestinal dMyc modulates lifespan in a diet-dependent manner.

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posted on 01.11.2018, 17:36 by Kazutaka Akagi, Kenneth A. Wilson, Subhash D. Katewa, Mauricio Ortega, Jesse Simons, Tyler A. Hilsabeck, Subir Kapuria, Amit Sharma, Heinrich Jasper, Pankaj Kapahi

(A-C) Kaplan-Meier survival analysis of tissue-specific knockdown of dMyc upon AL and DR. (A) Enteroblasts and enterocytes (5966-GS>dMyc RNAi), (B) Intestinal stem cells and enteroblasts (5961-GS>dMyc RNAi), (C) Fat bodies (S1106-GS>dMyc RNAi). (D) Median lifespan calculated from A-C are shown. Statistical analysis of the survival curves and the number of flies are provided in S2, S3 and S4 Tables. See also S1 Fig.