Interaction network analysis for DEGs post 2 h (A) and 8 h (B) LPS stimulation.
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posted on 2021-09-29, 17:30 authored by Pingan Chang, Hao Gao, Quan Sun, Xiaohong He, Feifei HuangColored nodes are proteins in the first shell of interactors. The edges indicate both functional and physical protein associations. Line thickness indicates the strength of data support. Empty and filled nodes are proteins of unknown and known or predicted 3D structures respectively.
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th2 cell differentiationreveal novel insightspolarized macrophages stimulatedknockout mouse macrophagesdistinct biological functionsbiological processes related8 h post2 h posttime quantitative pcrmajor pathways affectedmain pathways affectedlonger stimulation timedifferentially expressed genesm2 macrophage polarizationm1 macrophage polarizationdiv >< pampk signaling pathwayaffected genessignaling pathwayfirst timeresponsive genesvarious stimulitranscriptome analysisnos1 signalinglike receptorearly stagedifferent stagesclassically activatedalternatively activated
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