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Inhibition of ACC invasion promoted by CAFs.

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posted on 2016-03-08, 08:15 authored by Jiao Li, Zhuqiang Jia, Jing Kong, Fuyin Zhang, Shimeng Fang, Xiaojie Li, Wuwei Li, Xuesong Yang, Yong Luo, Bingcheng Lin, Tingjiao Liu

(A) GM6001 inhibited both SACC-LM and SACC-83 invasion promoted by CAF-A1 and CAF-A2. (B) CXCL12 expression was confirmed in CAF-A1 and CAF-A2. NF showed low CXCL12 expression. (C) AMD3100 inhibited SACC-LM and SACC-83 invasion led by CAFs. * P< 0.05, n = 3. Scale bar = 100 μm