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Download fileInferred avidity, serum IgG concentration, and HI titers by time after transplantation, immunosuppression grade, and cGVHD grade in 43 patients (197 samples in total).
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posted on 2022-01-31, 18:40 authored by Janina Linnik, Mohammedyaseen Syedbasha, Yvonne Hollenstein, Jörg Halter, Adrian Egli, Jörg StellingNote that data show one-dimensional associations, whereas regression analysis was performed with a high-dimensional model simultaneously accounting for time after transplantation, immunosuppression/cGVHD grade, and correcting for sex and age.
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sup >&# 8722provide quantitative insightslarger patient populationsexplains quantitative aspects>&# 961 ;</lower baseline aviditiescomplement experimental measurementsneutralizing antibody aviditiesmodel accurately describesmeasured hi titerslinked immunosorbent assaydiv >< pclassical hemagglutination inhibitionneutralizing antibody concentrationhemagglutination inhibitionneutralizing antibodiesinfer aviditiesestablish measurementsavidities inferredvaccinated patientsurea elutionterm protectionstudy demonstratespipetting errorsp </model predictedmodel correlatedimportant parametersimmunosuppressive treatmentigg concentrationshi titerhi assayfirst principlesestablishing longdisentangle causesdetection limitbiophysical modellingbiophysical modelbased inferenceapproach requiresagglutination assays70 ],
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