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Infectious Keratitis Dataset Based on Multimodal Slit-Lamp Images

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posted on 2025-03-18, 07:35 authored by FenFen LiFenFen Li

Dataset inclusion criteria: The dataset included slit-lamp images of all patients diagnosed with corneal diseases at two hospitals between 2018 and 2023. These images were captured using a digital slit-lamp camera with three illumination modalities: slit-beam imaging, diffuse white light, and diffuse cobalt blue light with fluorescein staining. Patients were included if they met any of the following criteria: (1) images from patients with active corneal infections; (2) patients diagnosed with herpes simplex keratitis (HSK) by three corneal specialists based on medical history, clinical manifestations, and effective response to empirical antiviral therapy; (3) bacterial keratitis (BK), fungal keratitis (FK), and Acanthamoeba keratitis (AK), defined as having compatible clinical manifestations with at least one positive laboratory test (smear or microbial culture). In addition to the categories of corneal infections, images from patients with other corneal diseases that have similar visual features were classified into the "other" group, including various corneal dystrophies, filamentous keratitis, corneal opacities (COs), and corneal degeneration.

Dataset details: The dataset from Zhejiang Eye Hospital consists of 475 ocular images from 380 eyes. Among these, 124 were HSK, 35 were BK, 24 were FK, and 197 were other corneal abnormalities. The dataset from Aier Guangming Eye Hospital includes 429 ocular images from 239 patients. Among these, 74 were HSK, 27 were BK, 9 were FK, and 129 were other corneal abnormalities.

Funding

National Natural Science Foundation of China (62276210)

Key Research and Development Program of Zhejiang Province (2024C04025)

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