pone.0221340.g003.tif (429.5 kB)

Imaging demonstrating the association between the expression of the hypoxia specific marker, hypoxia-inducible factor 1 alpha (HIF-1α) with Ktrans and Kep values.

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posted on 22.08.2019, 17:33 by Auni Lindgren, Maarit Anttila, Suvi Rautiainen, Otso Arponen, Kirsi Hämäläinen, Mervi Könönen, Ritva Vanninen, Hanna Sallinen

A) The association between HIF-1α expression with Ktrans L-ROI (P = 0.021 B) with Ktrans S-ROI (P = 0.018) C) with Kep L-ROI (P = 0.032) and D) with Kep S-ROI (P = 0.033). The HIF-1α expression dichotomized into low and high using the median immunoreactive score as the cutoff value.