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Histopathology of PDGFA/p53 shRNA-driven brain tumors.

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posted on 30.03.2017, 18:01 authored by Nina P. Connolly, Jesse A. Stokum, Craig S. Schneider, Tatsuya Ozawa, Su Xu, Rebeca Galisteo, Rudolph J. Castellani, Anthony J. Kim, J. Marc Simard, Jeffrey A. Winkles, Eric C. Holland, Graeme F. Woodworth

(A) Hematoxylin and eosin staining of whole brain slice with colored boxes highlighting areas of particular interest. (B) Red box = representative sample taken from the invasive edge of the tumor. Arrowheads indicate tumor invasion into adjacent brain tissue. (C) Blue box = hypercellular tumor with regions of pseudopallisading necrosis. (D) Yellow box = areas of microvascular proliferation, hypercellularity, and pleomorphism. (Scale bar = 200 μm).