Histomorphometric quantification of H & E -stained lungs from the 4T1 model from SCID integrin α11 wild type (WT) (n = 4) and SCID integrin α11-deficient (α11-KO) (n = 5) mice.
Average number of metastasis per section (A) and average area per section (B) is shown. The horizontal lines indicate the mean values. No significant differences were observed (p = 0.73 and p = 0.79) using Mann U Whitney t-test and unpaired two-tailed t-test, respectively. A representative lung with metastasis from a WT mouse is shown (C, D). Scale bar indicates 100 μm.