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Histomorphometric quantification of H & E -stained lungs from the 4T1 model from SCID integrin α11 wild type (WT) (n = 4) and SCID integrin α11-deficient (α11-KO) (n = 5) mice.

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posted on 18.03.2016, 13:13 by Inga Reigstad, Hilde Y. H. Smeland, Trude Skogstrand, Kristina Sortland, Marei Caroline Schmid, Rolf K. Reed, Linda Stuhr

Average number of metastasis per section (A) and average area per section (B) is shown. The horizontal lines indicate the mean values. No significant differences were observed (p = 0.73 and p = 0.79) using Mann U Whitney t-test and unpaired two-tailed t-test, respectively. A representative lung with metastasis from a WT mouse is shown (C, D). Scale bar indicates 100 μm.