pone.0269924.g004.tif (5.59 MB)
Histological changes in spinal cords after intraperitoneal LPS administration.
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posted on 2022-06-13, 17:27 authored by Akiko Hirotsu, Mariko Miyao, Kenichiro Tatsumi, Tomoharu TanakaHigh-magnification images of Fig 3 are shown. Arrows indicate edematous changes of the anterior column and arrowheads depict densely stained cells. Scale bars, 50 μm (×400).
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show significant changeintraperitoneally injected miceinflammatory cytokine upregulationincluding microglial activationimmunostaining analyses showedcurrent results indicatecentral nervous systemwhite matter edemainduced cerebral disordersglobal edematous changesimmunohistochemical changesgray matterdrastically inducedspinal microgliaspinal cordsignificantly activatedpresent studyinvestigate molecularespecially aroundanterior hornsanterior columnanother component
