HDAC2 inhibition reversed the memory impairment caused by maternal isoflurane exposure.
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(a) Target quadrant traveling time. The target quadrant traveling time in SAHA treated sugroup was significant more than relative non-SAHA subgroups (* p < 0.05); The traveling time in I2S, I4S and I8S group was not significantly different from that in CN group. (b) Platform crossing times. The platform-crossing times in SAHA treated sugroups increased compared with their relative non-SAHA subgroups, but had no statistical differences. The platform-crossing times in I8S subgroup was still less than CN group (* p < 0.05).