pone.0221509.g003.tif (3.61 MB)
Download file

Grouping of networks based on functionally enriched GO terms.

Download (3.61 MB)
posted on 2019-08-22, 17:37 authored by Sandra Isabel Calderon-Rodríguez, María Carolina Sanabria-Salas, Adriana Umaña-Perez

The functionally grouped network of enriched categories was generated for the differential proteins using ClueGO. GO terms are represented as nodes, the edges connecting the nodes are based on the kappa statistic that measures the overlap of shared genes between terms (less to 0.4). The node size indicates the number of proteins mapped to each term and the color represents the term enrichment significance. Only the most significant term in the group is labeled. Functionally related groups partially overlap. Visualization has been carried out using Cytoscape 3.4.0.