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Graphical representation of the community of B. adolescentis ATCC 15703 and F. prausnitzii A2–165 after the application of the community gap-filling method.

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posted on 01.11.2021, 17:36 by Dafni Giannari, Cleo Hanchen Ho, Radhakrishnan Mahadevan

The best solution calculated by the community gap-filling algorithm predicted that the metabolic models of the strains B. adolescentis ATCC 15703 and F. prausnitzii A2–165 share the available Glucose from the common medium and produce lactate (LAC), formate (FOR), and butyrate (BUT), while they exchange acetate (AC), and amino acids (3 letter code). The non-dashed arrows represent intracellular metabolite flow and the dashed arrows represent the exchange reactions of SCFAs and amino acids. The thickness of the dashed arrows represents the relative order of magnitude of the calculated fluxes for the exchange reactions.