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Grail suppresses the expression of pro-inflammatory cytokines in LPS-stimulated RAW264.7 cells.

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posted on 2018-12-20, 18:28 authored by Chih-Chin Shih, Pei-Yao Liu, Jye-Hann Chen, Mei-Hui Liao, Chih-Ming Hsieh, Shuk-Man Ka, Chin-Chen Wu, Hui-Tsu Lin, Ti-Hui Wu, Ying-Chuan Chen

The mRNA expression of (A) Grail, (B) IL-1β, and (C) TNF-α was evaluated in RAW264.7/Vector and RAW264.7/shGrail cells after LPS stimulation (3 h; 100 ng/ml). In contrast, the effects of Grail overexpression on the mRNA expression of (D) Grail, (E) IL-1β, (F) TNF-α, and (G) IL-6 were examined in RAW264.7 cells after LPS stimulation (3 h; 100 ng/ml). These data are presented as the mean ± SEM. A student’s t-test was used to assess statistical significance. ***P < 0.001.

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