Grading of vitreous HRF based on fundus and OCT images.

Grade 0 was characterized by no or very few HRF. Grade 1 showed significantly more HRF in the vitreous (red arrows) seen in OCT images only. Grade 2 and 3 were characterized by clumping of vitreous HRF (red circles) creating a ‘window effect’ that obstructed the view of the underlying retina in both fundus and OCT images. Vitreous HRF were classified as grade 2 if HRF formed clumps obstructing up to 25% of the fundus and OCT image area with grade 3 referring to HRF clumps obstructing more than 25% of the fundus and OCT images.