Fig 2.jpg (146.86 kB)
Genetic Confounding
Version 2 2020-10-19, 20:09
Version 1 2020-08-01, 17:31
figure
posted on 2020-10-19, 20:09 authored by Sara HartSara Hart, Callie LittleCallie Little, Elsje van BergenElsje van BergenAn
example of how genetic confounding works (note, only one parent drawn, for
simplicity). Parents share genes related to reading ability with their
children, and also control the number of books in their home. This creates
gene-environment interplay. It is important to note that the environmental
effect may still have a causal role, even with gene-environment interplay. If
genes play a role but are not modeled (as in Figure 1), the correlation between
the environmental measure and the child’s trait is genetically confounded.
Here, the role of genes is modeled, allowing for an estimation of the genetic effect
and the environmental effect.