Functional enrichment analysis of DEmRNAs in fetal side placental tissue of PCOS and control group.

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posted on 2024-03-21, 19:54 authored by Ningning Xie, Fangfang Wang, Danqing Chen, Jue Zhou, Jian Xu, Fan Qu

(A) Bubble plot of enriched top 20 cell components (CC) terms ranking by rich factor. Enriched terms of (B) B cell receptor signaling pathway and (C) natural killer cell mediated cytotoxicity in Gene Set Enrichment Analysis (GSEA) analysis.

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underlying molecular mechanisms significant changes observed related cerna networks predict potential drugs potential drug candidates polycystic ovary syndrome may impact fetal lncrnas expression levels identified 308 demrnas emerging evidence suggests 57 cerna events placental cerna networks functional enrichment analysis immune dysfunction mediated placental growth factor div >< p fetal immune system identifying hub genes whether immune function protein interaction network pcos group ),placental growth immune system hub genes pcos ),gsea analysis control group eight genes transcriptome sequencing study represents significantly elevated reproductive years reactive protein pcos tissues pcos therapy pcos samples neutrophil count lymphocyte count jun indicating alterations inaugural attempt hypersensitive c fos finally obtained egr1 dramatically decreased cxcr2 cxcr1 cxcl8 cxcl11 cxcl10 currently unexplored connectivity map conducted utilizing common endocrine chemokine pathway 77 demirnas 332 delncrnas

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Functional enrichment analysis of DEmRNAs in fetal side placental tissue of PCOS and control group.

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