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Fraction of putative essential genes among genes of the same degree

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posted on 2011-12-30, 20:37 authored by Jodi R Parrish, Jingkai Yu, Guozhen Liu, Julie A Hines, Jason E Chan, Bernie A Mangiola, Huamei Zhang, Svetlana Pacifico, Farshad Fotouhi, Victor J DiRita, Trey Ideker, Phillip Andrews, Russell L Finley
genes in the higher confidence interaction map (confidence score > 0.5) were collected into different groups according to their degrees (number of interacting partners). For each degree group the fraction of putative essential genes was computed and plotted as shown. Solid lines in the graphs were fitted using the available data points. The r-values represent Pearson correlation coefficients between fractions of putative essential genes and their degrees. Putative essential genes are orthologs of genes identified as essential by Baba ., [76]. Putative essential genes are orthologs of genes identified as essential by Kobayashi ., [75]. Putative essential genes are the intersection of genes predicted to be essential from the and sets. Putative essential genes are the union of the and sets.

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Taken from "A proteome-wide protein interaction map for "

http://genomebiology.com/2007/8/7/R130

Genome Biology 2007;8(7):R130-R130.

Published online 5 Jul 2007

PMCID:PMC2323224.

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