Fig 1 -

(A) Volcano plot of differentially expressed genes in lesional versus non-lesional tissue in Hidradenitis Suppurativa. Fold change pertains to expression in lesional versus non-lesional tissue. Genes pertaining to fibroblasts and fibroblast associated gene expression are highlighted including MMP (Matrix metalloproteinase) 1 and 3, Oncostatin M (OSM), transforming growth factor Beta 1 (TGFB1), vimentin (VIM) and Dipeptidyl protease 4 (DPP4). (B): Pathway analysis by PANTHER demonstrating enrichment of pathways pertaining to tissue remodeling, metalloproteinase activity and other extracellular matrix and fibroblast associated functions in lesional, versus non lesional tissue in HS.