1/1
Fetal cardiac cine imaging from motion-corrected super-resolution reconstruction of highly-accelerated real-time MRI
Motion is a key limiting factor in fetal cardiac MRI as the small, rapidly beating heart is subject to various periodic and spontaneous motions. Highly accelerated real-time imaging with high temporal resolution was used to obtain serial ‘snapshots’ of the fetal heart and surrounding anatomy that could be motion-corrected and reassembled, combining several cardiac cycles into a single heartbeat. A super-resolution reconstruction was applied to increase the visibility of dynamic anatomical features in the densely sampled data. The resulting cine images provide a clear depiction of dynamic cardiac features.
abstract: http://cds.ismrm.org/protected/16MPresentations/abstracts/0458.html
Figure 1 Representative x-f space at the location of the fetal heart from (a) aliased, under-sampled data, and (b) reconstructed real-time images, with (c) location of x indicated in DC x-f image.
Figure 2 Reconstructed real-time (a) full field-of-view image with (b) line-profile from dashed line through fetal heart showing pulsation of the ventricles and (c) maternal respiratory self-gating signal and gated frames in a 32 week gestational age pregnancy.
Figure 3 Reconstructed cine image frames at (a) ventricular end-systole and (b) end-diastole. In systole, shortening and thickening of the myocardium can be seen as the ventricles contract against closed atrioventricular valves (TV, MV), while the valves are open as the ventricles fill in diastole. A mitral valve papillary muscle (PM) is also depicted, and the foramen ovale (FO) is clearly visible between the atria. The descending aorta (Ao) and bilateral pulmonary veins (PV) are also seen.
Figure 4 Animated video of fetal cardiac cine imaging from motion-corrected super-resolution reconstruction of highly-accelerated real-time MRI.
