pone.0233109.g006.tif (721.84 kB)
Expression or rank difference between groups of HIF1α normalised to a) 18S, b) GAPDH, c) PABPN1×HMBS, d) ACTB×PABPN1 in the cisplatin treated groups.
figureposted on 2020-05-21, 17:41 authored by Sanjeeva Herath, Hongying Dai, Jonathan Erlich, Amy YM Au, Kylie Taylor, Lena Succar, Zoltán H. Endre
Data are means (one-way ANOVA) or medians (Kruskal Wallis) and 95% CI (n ≥ 6). * p < 0.05, ** p < 0.01, *** p < 0.001.
candidate normalisation geneKIMACTBGAPDHglyceraldehyde 3- phosphate dehydrogenasekidney disease Normalisationtoxicological kidney modelsintra-class correlation coefficientgene expressionsample size calculation10 candidate reference genesPECAMpolymerase chain reactionPABPNgenes 18 STGFHIFGOIkidney cell typesReduced within-group variationreference genesreference gene stability