Expression of ST2L and sST2 in pancreatic cancer cell lines.
figureposted on 27.04.2020, 17:29 by Keizo Takenaga, Miho Akimoto, Nobuko Koshikawa, Hiroki Nagase
qRT-PCR analysis of the expression of ST2L and sST2. The expression level was normalized to that of GAPDH. (A) Human pancreatic cancer cell lines. (B) Mouse pancreatic cancer Panc02 cells.
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modulates IL -33-STmouse pancreatic cancer cell linesmouse pancreatic cancer Panc 02 cellsreceptor ST 2Lpancreatic cancer cellsCxcl 3 expressioncolon cancer cellsCXCL 3mRNA expression levelsCXCL 3-CXCR axisPCRpancreatic cancersST 2-expressing mouse pancreatic cancer Panc 02 cellstumor microenvironmentConclusions Cancer cell-derived sST 2Methods ST 2cancer cell-derived interleukin -33 decoy receptor sST 2IL -33 decoy receptor sST 2orthotopic tumor growthsST 2 secretionMPOtumor growthshRNA-resistant sST 2 mRNAsST 2sST 2 expressionELISAIL -33 knockout miceSBC 57BL micemurine pancreatic cancer model Background Proinflammatory interleukin -33tumor tissuesIL -33-ST