Exometabolite concentrations of acetate, lactate and formate produced by S. Typhimurium within macrophages and epithelial cells.

Concentrations of acetate lactate and formate are shown for all host cell lines for the S. Typhimurium parent strain (4/74) or ΔptaΔackA strain as indicated. The data was corrected for exometabolite production by uninfected host cells. Error bars represent the standard deviation from at least three independent biological replicates performed on separate days and significant differences between infected and uninfected medium is indicated by asterisks, as follows: no asterisk, P > 0.05; *, P < 0.05; **, P < 0.01; and ***, P < 0.001. The data is presented as average concentrations of exometabolite produced per bacterial cell, per hour.