Effects of live and HK Leuconostoc mesenteroides on liver function in CKD mice.
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posted on 2025-02-24, 18:43 authored by Fittree Hayeeawaema, Natthawan Sermwittayawong, Chittipong Tipbunjong, Nawiya Huipao, Paradorn Muangnil, Pissared KhuituanThe liver function was investigated by enzyme levels after the treatment period. A, B, and C: The AST, ALT, and ALP levels, respectively. CKD; chronic kidney disease, LLp; live Lactiplantibacillus plantarum, HKLp; Heat-killed Lactiplantibacillus plantarum, LLn.m; Live Leuconostoc mesenteroides, and HKLn.m; Leuconostoc mesenteroides. Data were shown as mean ± SEM (n = 7–10). #p < 0.05 when compared to the control group; *p < 0.05 and **p < 0.01 when compared to the CKD group (one-way ANOVA repeated by Bonferroni test).
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restored gut microbiotaincluding glomerular necrosischain fatty acidsleuconostoc mesenteroides known therapeutic agentskidney damage observeddiv >< pinduced gastrointestinal dysfunctionsignificantly reduced buncreatinine levels comparedckd mice comparedcontrol mice (<ckd mice (<gastrointestinal dysfunction treatmentintestinal environment modulationgastrointestinal dysfunctioncontrol micep intestinal environmentcreatinine levelsckd micetherapeutic potentialgastrointestinal functionstubular dilatationstudy aimedrenal damageprobiotic potentialnatural sourceshemolytic activityfindings highlightbacteroidota populationsantibiotic sensitivity05 ).05 ),
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