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Effects of intravenous methacholine infusion on auto-positive end-expiratory pressure (auto-PEEP), end-expiratory transpulmonary pressure (Ptp, exp), and end-expiratory abdominal pressure (Pabd, exp)

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posted on 30.12.2011, 22:50 by Adelaida M Miro, Michael R Pinsky, Paul L Rogers

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Taken from "Effects of the components of positive airway pressure on work of breathing during bronchospasm"

Critical Care 2004;8(2):R72-R81.

Published online 9 Feb 2004

PMCID:PMC420031.

Copyright © 2004 Miro et al., licensee BioMed Central Ltd. This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the article's original URL.

Methacholine induced no significant hyperinflation according to the auto-PEEP and Ptp, exp measurements. However, expiratory muscle activity significantly increased after methacholine administration, as demonstrated by the increase in Pabd, exp. *< 0.01.

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