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Effects of UPs on phosphorylation of p38 and ERK MAPKs

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posted on 30.12.2011 by Zhuowei Li, Jacqueline D. Carter, Lisa A. Dailey, Yuh-Chin T. Huang

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Taken from "Pollutant Particles Produce Vasoconstriction and Enhance MAPK Signaling via Angiotensin Type I Receptor"

Environmental Health Perspectives 2005;113(8):1009-1014.

Published online 15 Apr 2005


This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the article's original DOI.

Time-dependent increase in phospho-ERK1/2 (p-ERK1/2; ) and phospho-p38 (p-p38; ); confluent cells were treated with 10 μg/mL UPs for up to 20 min. Dose-dependent increase in p-ERK1/2 () and p-p38 (); cells were treated with 1, 10, and 100 μg/mL UPs for 10 min. Cell lysates (50 μg) were separated by 10% SDS-PAGE gel and immunoblotted with monoclonal antibodies against p-p38 or ERK1/2 as described in “Materials and Methods.” Results are representative of three independent experiments.