Effects of Phb1 expression level and LPS stimulation on inflammatory cytokines in RAW 264.7 cells with Phb1 knockdown.
figureposted on 2020-11-11, 18:36 authored by Soohan Jung, Jaehee Park, Kwang Suk Ko
A: TNF-α, B: IL-6, C: IL-1α, D: IL-1β, E: IL-10. Values represent means ± SE of three replicate experiments performed with independent cultures. * Indicate significant differences by one-way ANOVA (p<0.05).
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Phb 1NF -κBPhb 1 knockdown RAW 264.7 cellsLPS-treated RAW 264.7 cellsmitochondrial protein stabilizationProhibitin 1 deficiencyNF -κB activationLPS-stimulated RAW 264.7 cellsLuciferase reporter assaycell cycle regulationPhb 1 expression levelmurine macrophages Prohibitin 1Phb 1 mRNANF -κB luciferase activityILSAMe treatment attenuatedPhb 1 knockdown macrophage cellsluciferase reporter assayTNF