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Effect of putrescine and all-retinoic acid (ATRA) on immature dendritic cell (DC) phenotype

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posted on 31.12.2011, 00:01 by Alban Gervais, Jean Levêque, Françoise Bouet-Toussaint, Florence Burtin, Thierry Lesimple, Laurent Sulpice, Jean-Jacques Patard, Noelle Genetet, Véronique Catros-Quemener

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Taken from "Dendritic cells are defective in breast cancer patients: a potential role for polyamine in this immunodeficiency"

Breast Cancer Research 2005;7(3):R326-R335.

Published online 25 Feb 2005

PMCID:PMC1143555.

Copyright © 2005 Gervais et al.; licensee BioMed Central Ltd

Cells were collected after immature DC preparation procedure (imm DC; = 11) and treated with 10 mmol/l putrescine (Put; = 10). To putrescine-treated DCs was added 1 μmol/l ATRA (Put + ATRA; = 5). Data are expressed as percentage of cells (with standard error) expressing the HLA-DRLinand HLA-DRLinphenotypes. *< 0.01 versus imm DCs; **< 0.02 versus putrescine-treated imm DCs.

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