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Effect of plant antimicrobial compounds on MDR gene expression.

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posted on 2019-06-25, 17:43 authored by Saray Santamaría-Hernando, Marta Senovilla, Almudena González-Mula, Pedro Manuel Martínez-García, Sandra Nebreda, Pablo Rodríguez-Palenzuela, Emilia López-Solanilla, José Juan Rodríguez-Herva

Differential gene expression was evaluated by RT-qPCR after PsPto cells were grown in the presence of 0.5 mM of the indicated compounds (solved in DMSO) or DMSO. Cell samples were harvested at the mid exponential growth phase (OD600 = 0.5). Bars represent relative expression changes of target genes in cells grown in the presence of antimicrobial compounds with respect to DMSO-grown cells. Data represent means and standard errors of three replicates, with different letters indicating significant differences among treatments (p < 0.05, Fisher’s LSD test).