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Effect of cytokines on the expression of genes for matrix metalloproteinases (MMPs) and MMP-related genes

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posted on 2011-12-30, 23:35 authored by Dirk Nagorsen, Sara Deola, Kina Smith, Ena Wang, Vladia Monsurro, Paola Zanovello, Francesco M Marincola, Monica C Panelli

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Taken from "Polarized monocyte response to cytokine stimulation"

Genome Biology 2005;6(2):R15-R15.

Published online 21 Jan 2005


Copyright © 2005 Nagorsen et al.; licensee BioMed Central Ltd.

MMP genes and MMP-related genes (such as disintegrins, IFN-γ and related genes, IFN-α, α-defensins, TGF-β, TNF-α, IGF-1, EGF, FGF, IL-1, MCP-3 - complete list available from the authors on request) were clustered according to the alternative and classical groups and filtered for 70% presence and at least one value equal to or greater than a 1.5-fold change in expression (a total of 36 genes). The clusterogram displays 11 of the most representative genes. Color coding is as Figure 2.


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