Effect of UDCA on wound healing contraction.
Two full thickness cutaneous wounds (6mm in diameter) were cut in male Swiss mice. Photos of wounds were captured every day starting from day 0 (wounding). Animals were treated with either vehicle (left wound) or UDCA (500 μM cream, right wound) for 10 consecutive days. The line graph represents the mean of percent change relative to original wound size ± SE median (n = 6). *P<0.05: significantly different versus vehicle-treated (dashed line) wounds in the same time point. UDCA: ursodeoxycholic acid.