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Effect of CSE on vitamin D metabolism in THP-1 macrophages.

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posted on 2016-08-11, 17:52 authored by Nele Heulens, Hannelie Korf, Carolien Mathyssen, Stephanie Everaerts, Elien De Smidt, Christophe Dooms, Jonas Yserbyt, Conny Gysemans, Ghislaine Gayan-Ramirez, Chantal Mathieu, Wim Janssens

THP-1 macrophages were stimulated for 16h with 10% CSE or vehicle, followed by an additional stimulation for 24h with 10 nM 1,25(OH)2D or vehicle. mRNA expression levels of (A) VDR, (B) CYP27B1 and (C) CYP24A1 were determined in cell lysates. mean±SEM. *p<0.05, ***p<0.001