Dynamics of plasma and stool intestinal damage biomarkers during primary HIV-infection (PHI).

Dynamics of plasma biomarkers associated with intestinal damage (A) and dynamics of stool biomarkers associated with innate immunity (B) and intestinal permeability (C) are shown. Relative changes (Z-score) of the biomarker levels during PHI with respect to the HIV-uninfected group have been represented by a transformation of the fitted longitudinal models after subtracting the mean and dividing by the standard deviation of HIV-non infected distribution. Values were logarithmic transformed in the cases where it was required to correct non-normal distributions.