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Distributions of log10 Month 13 MN (Panels A, C, E, G) and PRNT50 (Panels B, D, F, H) titers in CYD14 participants (all ages = 2 to 14 years old), stratified by treatment group and case status (serotype-matched vs serotype-mismatched cases).

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posted on 2020-06-15, 20:04 authored by Lindsay N. Carpp, Youyi Fong, Matthew Bonaparte, Zoe Moodie, Michal Juraska, Ying Huang, Brenda Price, Yingying Zhuang, Jason Shao, Lingyi Zheng, Laurent Chambonneau, Robert Small, Saranya Sridhar, Carlos A. DiazGranados, Peter B. Gilbert

The gray horizontal shaded band denotes the middle third of nAb responses (log10 MN titer = 1.23 − 2.03; log10 PRNT50 titer 1.76 − 2.42). A “matched-serotype case” is one where the VCD-causing virus was of the same serotype as the virus used in the nAb assay; a “nonmatched-serotype case” is one where the VCD-causing virus was of a different serotype than the virus used in the nAb assay.

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