Differential expressed gene analysis reveals CMS-specific differences between BMI groups.

(A) Euler diagrams were used to visualize the weighted overlap of DESeq2-obtained DEGs (MeanBase > 10, FDR p value < 0.05) between Obese vs. Normal, Obese vs. Overweight, and Overweight vs Normal DEGs for each CMS category. The R package eulerr was used to construct the Euler diagrams. (B) Upset plots were used to visualize the intersection of DEGs between the four CMS categories for each BMI comparison. The R package UpsetR was used to construct the Upset plots.