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Diagnostic capability of DCP for detecting early HCC with a solitary tumor smaller than 3cm.

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posted on 12.04.2016, 14:11 authored by Jun Ji, Hao Wang, Yan Li, Lei Zheng, Yuepeng Yin, Zhenzhen Zou, Feiguo Zhou, Weiping Zhou, Feng Shen, Chunfang Gao

(A and B) The concentrations of serum DCP in HCC according to tumor size (<3cm, ≥3 and ≤5cm, >5 and ≤10cm, or >10cm). (C and D) ROC curves of DCP, AFP, or their combination in HCC with a solitary small tumor (≤3cm) versus all controls (HCs and DC). (E and F) ROC curves of DCP, AFP, or their combination in HCC with a solitary small tumor (≤3cm) versus disease controls (G and H). The positive rates of serum DCP and AFP in HCC according to tumor size (<3cm, ≥3 and ≤5cm, >5 and ≤10cm, or >10cm). DCP, des-gamma-carboxy prothrombin; AFP, alpha-fetoprotein; HCC, hepatocellular carcinoma; HC, healthy control; DC, disease control; ROC, receiver operating characteristics; AUC, area under the curve; 95% CI, 95% confidence interval.

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