pone.0236666.g003.tif (1.48 MB)
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Detecting intra-chromosomal interactions at the 3’HS1 region.

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posted on 31.07.2020, 17:23 authored by Yong Chen, Yunfei Wang, Xin Liu, Jian Xu, Michael Q. Zhang

A. The identified long-range interactions are shown together with DHS, histone markers (H3K27ac, H3K4me1 and H3K36me3), CTCF, RAD21 and SMC3 binding signals from the ENCODE database. Comparisons with 5C, in situ Hi-C, RNAPII and CTCF ChIA-PET are shown on the bottom. The arrows indicate the peak signals of DHS and H3K4me1 that co-localize with the interactions at the 3’ region of the OR51B4 gene. B. ChIP-seq data of 33 TFs are shown. The right blue bar denotes the 17 TF tracks with strong binding peaks at the 3’ region of the OR51B4 gene (Chr11:5310800–5320000).