Deciphering downstream gene targets of PI3K/mTOR/p70S6K pathway in breast cancer-3
figureposted on 31.12.2011, 20:38 by Henna Heinonen, Anni Nieminen, Matti Saarela, Anne Kallioniemi, Juha Klefström, Sampsa Hautaniemi, Outi Monni
R 24 hours and the protein expression of eIF4G1 was detected by Western immunoblotting. The plus (+) sign indicates the inhibitor-treated sample and the minus (-) sign the non-treated sample. A) Rapamycin and B) Ly294002 downregulated eIF4G1 expression at protein level in BT-474 and SK-BR-3 cells, respectively. Beta-actin was used as a loading control.
Taken from "Deciphering downstream gene targets of PI3K/mTOR/p70S6K pathway in breast cancer"
BMC Genomics 2008;9():348-348.
Published online 24 Jul 2008