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DSGC spiking properties.

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posted on 2021-12-30, 18:31 authored by Elishai Ezra-Tsur, Oren Amsalem, Lea Ankri, Pritish Patil, Idan Segev, Michal Rivlin-Etzion

a. Example intracellular current-clamp recordings from a DSGC in response to presentation of a 2-sec bright spot (100 μm diameter). One repetition is shown in black, superimposed on nine other repetitions in grey. The Blue horizontal line denotes the baseline voltage of the cell (average of all traces), and the red line indicates the threshold for spiking. b. Average waveform of all cells (n = 15 DSGCs), aligned to the peak of the first spike evoked in response to spots presentation. c, d. Same as (a, b) but with gabazine application (5 μm; n = 10 DSGCs). Note that while resting potential increased in the presence of the GABA blocker, the spike threshold did not change.