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Cytokine levels in the cortex of TG and WT mice 9 months post-irradiation.

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posted on 2017-11-29, 18:23 authored by Emil Rudobeck, John A. Bellone, Attila Szücs, Kristine Bonnick, Shalini Mehrotra-Carter, Jerome Badaut, Gregory A. Nelson, Richard E. Hartman, Roman Vlkolinský

Expression of CXCL10 and CCL2 was significantly higher in TG mice than in WT mice, but irradiation had no further effect on these cytokines. The differences in TNFα, IL-1β and IL-6 expression were not statistically significant (NS) in either TG or WT mice. TG mice: N = 6, 6, 5, 5 animals/radiation group; WT mice: N = 7, 8 animals/radiation group. Statistical analyses: 2-way ANOVA, genotype effect ††† p<0.001, † p<0.05. Data represent means ± SEM.