Cytokine levels in the cortex of TG and WT mice 9 months post-irradiation.
Expression of CXCL10 and CCL2 was significantly higher in TG mice than in WT mice, but irradiation had no further effect on these cytokines. The differences in TNFα, IL-1β and IL-6 expression were not statistically significant (NS) in either TG or WT mice. TG mice: N = 6, 6, 5, 5 animals/radiation group; WT mice: N = 7, 8 animals/radiation group. Statistical analyses: 2-way ANOVA, genotype effect ††† p<0.001, † p<0.05. Data represent means ± SEM.