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Creation of artificial recombinants with known breakpoints to test jpHMM and Simplot accuracy

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posted on 2011-12-31, 00:10 authored by Anne-Kathrin Schultz, Ming Zhang, Thomas Leitner, Carla Kuiken, Bette Korber, Burkhard Morgenstern, Mario Stanke

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Taken from "A jumping profile Hidden Markov Model and applications to recombination sites in HIV and HCV genomes"

BMC Bioinformatics 2006;7():265-265.

Published online 22 May 2006

PMCID:PMC1525204.

(A) The artificial recombinant, constructed from two different clades, has the actual breakpoints at every X-th nucleotide for = 500, 1000, 1500. Only the construction with = 1000 is shown here. (B) The phylogenetic tree demonstrates the relations and relative distances between the clades used in the artificial recombinants' construction.

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