Correlation between gene expression and average CpG methylation rates at CpG island shores.
Methylation rates in AD-related DMRs in CR1, CLU, and PICALM were plotted against the expression levels of CR1, CLU, and PICALM. Relationships were analyzed based on Pearson’s correlation coefficient. The numbers of samples examined are shown in parentheses. All methylation rates were quantified at the same regions as in Fig 2 by Sanger sequencing.