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Correlation between absolute changes in NAD+ concentration versus NR concentration.

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posted on 2017-12-06, 18:33 authored by Sophia E. Airhart, Laura M. Shireman, Linda J. Risler, Gail D. Anderson, G. A. Nagana Gowda, Daniel Raftery, Rong Tian, Danny D. Shen, Kevin D. O’Brien

Each subject is plotted as a different color. The blue line shows a linear regression of the change in NAD+ given the change in NR, and the shaded area shows the 95% confidence interval of that regression.

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An open-label, non-randomized study of the pharmacokinetics of the nutritional supplement nicotinamide riboside (NR) and its effects on blood NAD+ levels in healthy volunteers
PLOS ONEPLOS ONE

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NAD24- hour PK study1000 mg NRopen-label PK studyRecent murine studiessupplement nicotinamide riboside250 mg NR0. Whole-blood levelsNADHResults Oral NRblood nicotinamide adenine dinucleotidemitochondrial dysfunction

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