pone.0262574.g005.tif (405.45 kB)
Comparisons of the sensitivity and specificity of Bcftools and VarScan2 with different sample modes.
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posted on 2022-01-31, 18:24 authored by Jing Liu, Qingmiao Shen, Haigang BaoA: Comparisons of the sensitivity between Bcftools-single and Bcftools-multiple; B: Comparisons of the specificity between Bcftools-single and Bcftools-multiple; C: Comparisons of the sensitivity between VarScan2-single and VarScan2-multiple; and D: Comparisons of the specificity between VarScan2-single and VarScan2-multiple.
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wide association studiespopulation genetics analysesdifferent depth gradients50k snp arraythroughput ngs datahuman ngs datachicken ngs datasequencing depth greaterspecificities beyond 20xselect suitable pipelinesgenome analysis toolkitgeneration sequencing datahighest sensitivity numericallygatk ), bcftoolschickens pdetected snps increasedngs datasequencing depthgeneration sequencinghighest sensitivitysnp numberssnp arraysmany snpwidely usedtook advantagesixteen chickenspipeline increasedobvious changesobtain snpsfreebayes pipelinesfindings provideexcept freebayesexceed 20xdetecting snpscalling pipelinesbest choicebecome convenientalso genotyped