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Download fileComparison of trough plasma nevirapine concentration (μg/ml) during lead-in and steady state period.
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posted on 2017-08-21, 17:29 authored by Bindu Parachalil Gopalan, Kayur Mehta, Reena R. D'souza, Niharika Rajnala, Hemanth Kumar A. K., Geetha Ramachandran, Anita ShetThe difference between lead in (week1, 2) and steady state (week4) trough plasma nevirapine concentration (p = 0.034, p = 0.132) were assessed by Wilcoxon signed rank test.
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antiretroviral treatment initiationMedian nevirapine concentrationsHPLCtrough plasma nevirapine levelsdrug clearance ratesage-appropriate threshold nevirapine concentrationlead-in periodage 9 yearsSub-therapeutic nevirapine concentrationdose escalation strategydrug monitoring NevirapineART initiationHIVpediatric-focused dosing strategies