Comparison of the short-term effects of oral administration of OA (O OA), transdermal application of OA (TD OA) and CHQ-OA (TD CHQ-OA) pectin matrix patches with respective controls and a standard drug CHQ (D) on plasma insulin concentrations in P. berghei-infected rats with non-infected (NIC) and infected control (IC) animals.
figureposted on 2016-12-01, 18:02 authored by Happiness P. Sibiya, Musa V. Mabandla, Cephas T. Musabayane
Values are presented as means, and vertical bars indicate SEM of means (n = 30 in each treatment group).⋆p˂0.05 by comparison with non-infected control (NIC) animals, ♦p˂0.05 by comparison with infected control (IC) animals, ∞p˂0.05 by comparison with CHQ (O CHQ) treated animals.
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OA monotherapyCHQ-OA combination patchInfected control ratsblood glucose levelsglucose homeostasisCHQ-OA combination matrix patchonce-off transdermal applicationCHQ-OA combination pectin patchTransdermally Delivered OleanolicCHQ-OA combination therapy21- days periodBlood Glucose HomeostasisOral glucose testmalaria parasitesbergheiOGTblood glucose concentrations